The Effect of Beading and Permeable Axons on Water Diffusion Properties: A Monte Carlo Simulation of Axonal Degeneration and Its Effect on DTI and Q-space Contrasts

J. A. Farrell, B. A. Landman, J. Zhang, S. A. Smith, D. S. Reich, P. A. Calabresi, and P. C. van Zijl Dept. of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, Kennedy Krieger Institute, F.M. Kirby Research Center for Functional Brain Imaging, Baltimore, MD, United States, Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States, Electrical Engineering, Vanderbilt University, Nashville, TN, United States, Dept. of Radiology, Vanderbilt University, Nashville, TN, United States, Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, Neuroimmunology Branch (NINDS), National Institutes of Health, Bethesda, MD, United States, Dept. of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States